cusabio specializes in the production of antibody

Custom Recombinant Antibody

Custom Recombinant Antibody Production

Recombinant antibody, also known as genetic engineering antibody, refers to the usage of recombinant DNA and protein engineering technology to modify or recombine antibody genes according to various needs, then expressed after transfection via appropriate receptor cell.
Cusabio could offer one-stop service of recombinant antibody production to customers upon your various needs.
The production process of Cusabio custom recombinant antibody is as follows.

With 13+ years experience of antibody production, CUSABIO has developed and produced tens of thousands of quality antibodies for life science research. Currently, CUSABIO has established the HTP (high throughput) platform for recombinant antibody production, we specialized in antibody drug research and development that only provide services rather than drugs.

CUSABIO aims to offer rapid production service of recombinant antibodies to pharmaceutical companies, and enables them to pick out the “right” therapeutic antibodies in a short time with very competitive quotation.

Reference

CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit. Our products have been widely used by researchers in the worldwide. Now, we have listed a part of the publications citing our products, you can enter the catalog number to search the products what you want and see the corresponding reference.

cusabio specializes in the production of antibody

cusabio specializes in the production of antibody

Process & Deliverables:

Antigen Preparation Process Deliverables Production Time
Peptide Synthesis
  • Select Positive Gene
  • Recombinant Antibody Expression
  • Protein A/G Purification
  • ELISA, WB Validation
  1. QC report of antigen;
  2. 100ug×purified recombinant antibodies together with QC report, including the information of gene sequencing, concentration, purity and endotoxin content;
  3. WB positive guarantee for antigen;
  4. Other applications(IHC, IF, IP, FC, ChIP) could be available upon customers’ requests.
 8-16 weeks
Recombinant Protein Production 12-16 weeks
Native Protein Selection 12-16 weeks

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the small lymphocyte subtype. Mature B cells mainly reside in the lymph nodes in the superficial layer of the lymph node cortex and in the red and white nodes of the spleen. B cells can differentiate into plasma cells under the stimulation of antigens. Plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity of the body. In this article, we collect several question about B cell, and want to these information help you understand this kind of cell.

What is The Function of B Cell?

The function of B cell mainly includes two sections. On the one hand, they function in the humoral immunity component of the adaptive immune system by secreting antibodies. These antibodies serve as flags or the flares over a battle site. They recruit other defensive molecules in the bloodstream to the site, working toward killing the infection-causing organism. They also signal other immune cells to, in turn, wage war on the invader.

In addition to their essential role in humoral immunity, B cells also regulate many other functions essential for immune homeostasis. Of major importance, B cells are required for the initiation of T-cell immune responses by B cells antigen presenting and cytokines secreting. In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, and not from bone marrow as commonly believed.

What is The B Cell Differentiation?

The differentiation process of mammalian B cells can be divided into five stages: pre-B cells, immature B cells, mature B cells, activated B cells, and plasma cells. Among them, the differentiation of pre-B cells and immature B cells is antigen-untrusted, and the differentiation process is performed in the bone marrow. The antigen-dependent phase refers to mature B cells that are activated after antigen stimulation and continue to differentiate into plasma cells that synthesize and secrete antibodies. This stage of differentiation is mainly performed in peripheral immune organs.

Some of the activated B-cells become memory B-cells, which have very long lives in the bone marrow, lymph nodes and spleen. They remember the antigen they are specific for and are ready to respond quickly if they see it again. These are the cells that give us long-lasting immunity to different invaders. (Figure 1).

 

ERK2 recombinant monoclonal antibody
A5018 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human ERK2 for WB, IHC,ELISA

MEK1 recombinant monoclonal antibody
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Description: A recombinant monoclonal antibody from rabbit against human MEK1 for WB, IF, IHC,ELISA

HDAC6 recombinant monoclonal antibody
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TLR5 recombinant monoclonal antibody
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AKT1 recombinant monoclonal antibody
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Description: A recombinant monoclonal antibody from rabbit against human AKT1 for WB, IHC,ELISA

JAK2 recombinant monoclonal antibody
A5024 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human JAK2 for WB,ELISA

TLR9 recombinant monoclonal antibody
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EUR 595
Description: A recombinant monoclonal antibody from rabbit against human TLR9 for WB,ELISA

GAPDH recombinant monoclonal antibody
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Description: A recombinant monoclonal antibody from rabbit against human GAPDH for WB, IF, IHC,ELISA

PARP recombinant monoclonal antibody
A5037 100ul X 3
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Description: A recombinant monoclonal antibody from rabbit against human PARP for WB,ELISA

SIRT6 recombinant monoclonal antibody
A5039 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human SIRT6 for WB, IF,ELISA

ATF2 recombinant monoclonal antibody
A5041 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human ATF2 for WB,ELISA

STAT5a recombinant monoclonal antibody
A5042 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human STAT5a for WB,ELISA

Raf1 recombinant monoclonal antibody
A5043 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Raf1 for WB,ELISA

STAT2 recombinant monoclonal antibody
A5044 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human STAT2 for WB, IHC, IF,ELISA

STAT4 recombinant monoclonal antibody
A5045 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human STAT4 for WB,ELISA

SIRT1 recombinant monoclonal antibody
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EUR 595
Description: A recombinant monoclonal antibody from rabbit against human SIRT1 for WB, IF, IHC,ELISA

HMGB1 recombinant monoclonal antibody
A5052 100ul X 3
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Description: A recombinant monoclonal antibody from rabbit against human HMGB1 for WB, IF,ELISA

LEF1 recombinant monoclonal antibody
A5054 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human LEF1 for WB, IF, IHC,ELISA

CDK5 recombinant monoclonal antibody
A5055 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human CDK5 for WB, IF,ELISA

Rab4A recombinant monoclonal antibody
A5056 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Rab4A for WB, IHC,ELISA

Brd4 recombinant monoclonal antibody
A5058 100ul X 3
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Rab9 recombinant monoclonal antibody
A5063 100ul X 3
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Description: A recombinant monoclonal antibody from rabbit against human Rab9 for WB, IF,ELISA

Src recombinant monoclonal antibody
A5066 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Src for WB, IHC, IF,ELISA

CD4 recombinant monoclonal antibody
A5067 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human CD4 for WB,ELISA

Bak recombinant monoclonal antibody
A5068 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Bak for WB, IHC,ELISA

CD11a recombinant monoclonal antibody
A5069 100ul X 3
EUR 595
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