cusabio specializes in the production of antibody

Custom Recombinant Antibody

Custom Recombinant Antibody Production

Recombinant antibody, also known as genetic engineering antibody, refers to the usage of recombinant DNA and protein engineering technology to modify or recombine antibody genes according to various needs, then expressed after transfection via appropriate receptor cell.
Cusabio could offer one-stop service of recombinant antibody production to customers upon your various needs.
The production process of Cusabio custom recombinant antibody is as follows.

With 13+ years experience of antibody production, CUSABIO has developed and produced tens of thousands of quality antibodies for life science research. Currently, CUSABIO has established the HTP (high throughput) platform for recombinant antibody production, we specialized in antibody drug research and development that only provide services rather than drugs.

CUSABIO aims to offer rapid production service of recombinant antibodies to pharmaceutical companies, and enables them to pick out the “right” therapeutic antibodies in a short time with very competitive quotation.

Reference

CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit. Our products have been widely used by researchers in the worldwide. Now, we have listed a part of the publications citing our products, you can enter the catalog number to search the products what you want and see the corresponding reference.

cusabio specializes in the production of antibody

cusabio specializes in the production of antibody

Process & Deliverables:

Antigen Preparation Process Deliverables Production Time
Peptide Synthesis
  • Select Positive Gene
  • Recombinant Antibody Expression
  • Protein A/G Purification
  • ELISA, WB Validation
  1. QC report of antigen;
  2. 100ug×purified recombinant antibodies together with QC report, including the information of gene sequencing, concentration, purity and endotoxin content;
  3. WB positive guarantee for antigen;
  4. Other applications(IHC, IF, IP, FC, ChIP) could be available upon customers’ requests.
 8-16 weeks
Recombinant Protein Production 12-16 weeks
Native Protein Selection 12-16 weeks

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the small lymphocyte subtype. Mature B cells mainly reside in the lymph nodes in the superficial layer of the lymph node cortex and in the red and white nodes of the spleen. B cells can differentiate into plasma cells under the stimulation of antigens. Plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity of the body. In this article, we collect several question about B cell, and want to these information help you understand this kind of cell.

What is The Function of B Cell?

The function of B cell mainly includes two sections. On the one hand, they function in the humoral immunity component of the adaptive immune system by secreting antibodies. These antibodies serve as flags or the flares over a battle site. They recruit other defensive molecules in the bloodstream to the site, working toward killing the infection-causing organism. They also signal other immune cells to, in turn, wage war on the invader.

In addition to their essential role in humoral immunity, B cells also regulate many other functions essential for immune homeostasis. Of major importance, B cells are required for the initiation of T-cell immune responses by B cells antigen presenting and cytokines secreting. In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, and not from bone marrow as commonly believed.

What is The B Cell Differentiation?

The differentiation process of mammalian B cells can be divided into five stages: pre-B cells, immature B cells, mature B cells, activated B cells, and plasma cells. Among them, the differentiation of pre-B cells and immature B cells is antigen-untrusted, and the differentiation process is performed in the bone marrow. The antigen-dependent phase refers to mature B cells that are activated after antigen stimulation and continue to differentiate into plasma cells that synthesize and secrete antibodies. This stage of differentiation is mainly performed in peripheral immune organs.

Some of the activated B-cells become memory B-cells, which have very long lives in the bone marrow, lymph nodes and spleen. They remember the antigen they are specific for and are ready to respond quickly if they see it again. These are the cells that give us long-lasting immunity to different invaders. (Figure 1).

 

ENO1 recombinant monoclonal antibody
A5496 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ENO1 for WB, IF,ELISA

ACADM recombinant monoclonal antibody
A5498 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ACADM for WB, IHC, IF,ELISA

STIP1 recombinant monoclonal antibody
A5499 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human STIP1 for WB, IF,ELISA

TMEM173 recombinant monoclonal antibody
A5501 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human TMEM173 for WB,ELISA

Aldolase recombinant monoclonal antibody
A5502 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Aldolase for WB, IHC, IF,ELISA

RRM2 recombinant monoclonal antibody
A5504 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human RRM2 for WB, IF,ELISA

KPNA2 recombinant monoclonal antibody
A5505 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human KPNA2 for WB, IF,ELISA

DDAH1 recombinant monoclonal antibody
A5506 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human DDAH1 for WB, IHC,ELISA

Nogo recombinant monoclonal antibody
A5507 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Nogo for WB, IHC,ELISA

ALIX recombinant monoclonal antibody
A5508 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ALIX for WB,ELISA

TPOR recombinant monoclonal antibody
A5509 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human TPOR for WB,ELISA

YB1 recombinant monoclonal antibody
A5510 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human YB1 for WB, IHC, IF,ELISA

SMAD5 recombinant monoclonal antibody
A5511 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human SMAD5 for WB, IHC, IF,ELISA

S6K1 recombinant monoclonal antibody
A5512 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human S6K1 for WB,ELISA

ATF4 recombinant monoclonal antibody
A5514 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ATF4 for WB, IF,ELISA

GLUT3 recombinant monoclonal antibody
A5515 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human GLUT3 for WB,ELISA

Atg4A recombinant monoclonal antibody
A5516 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Atg4A for WB, IHC, IF,ELISA

NUP98 recombinant monoclonal antibody
A5520 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human NUP98 for WB, IF,ELISA

COX2 recombinant monoclonal antibody
A5523 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human COX2 for WB, IF,ELISA

CDCA5 recombinant monoclonal antibody
A5524 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CDCA5 for WB, IF,ELISA

Atg4C recombinant monoclonal antibody
A5528 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Atg4C for WB, IHC,ELISA

Wnt2b recombinant monoclonal antibody
A5529 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Wnt2b for WB, IF,ELISA

EIF4E recombinant monoclonal antibody
A5536 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human EIF4E for WB, IHC, IF,ELISA

PTBP2 recombinant monoclonal antibody
A5539 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PTBP2 for WB, IF,ELISA

Id1 recombinant monoclonal antibody
A5540 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Id1 for WB, IHC, IF,ELISA

TRAM2 recombinant monoclonal antibody
A5542 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human TRAM2 for WB ,ELISA