cusabio specializes in the production of antibody

Custom Recombinant Antibody

Custom Recombinant Antibody Production

Recombinant antibody, also known as genetic engineering antibody, refers to the usage of recombinant DNA and protein engineering technology to modify or recombine antibody genes according to various needs, then expressed after transfection via appropriate receptor cell.
Cusabio could offer one-stop service of recombinant antibody production to customers upon your various needs.
The production process of Cusabio custom recombinant antibody is as follows.

With 13+ years experience of antibody production, CUSABIO has developed and produced tens of thousands of quality antibodies for life science research. Currently, CUSABIO has established the HTP (high throughput) platform for recombinant antibody production, we specialized in antibody drug research and development that only provide services rather than drugs.

CUSABIO aims to offer rapid production service of recombinant antibodies to pharmaceutical companies, and enables them to pick out the “right” therapeutic antibodies in a short time with very competitive quotation.

Reference

CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit. Our products have been widely used by researchers in the worldwide. Now, we have listed a part of the publications citing our products, you can enter the catalog number to search the products what you want and see the corresponding reference.

cusabio specializes in the production of antibody

cusabio specializes in the production of antibody

Process & Deliverables:

Antigen Preparation Process Deliverables Production Time
Peptide Synthesis
  • Select Positive Gene
  • Recombinant Antibody Expression
  • Protein A/G Purification
  • ELISA, WB Validation
  1. QC report of antigen;
  2. 100ug×purified recombinant antibodies together with QC report, including the information of gene sequencing, concentration, purity and endotoxin content;
  3. WB positive guarantee for antigen;
  4. Other applications(IHC, IF, IP, FC, ChIP) could be available upon customers’ requests.
 8-16 weeks
Recombinant Protein Production 12-16 weeks
Native Protein Selection 12-16 weeks

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the small lymphocyte subtype. Mature B cells mainly reside in the lymph nodes in the superficial layer of the lymph node cortex and in the red and white nodes of the spleen. B cells can differentiate into plasma cells under the stimulation of antigens. Plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity of the body. In this article, we collect several question about B cell, and want to these information help you understand this kind of cell.

What is The Function of B Cell?

The function of B cell mainly includes two sections. On the one hand, they function in the humoral immunity component of the adaptive immune system by secreting antibodies. These antibodies serve as flags or the flares over a battle site. They recruit other defensive molecules in the bloodstream to the site, working toward killing the infection-causing organism. They also signal other immune cells to, in turn, wage war on the invader.

In addition to their essential role in humoral immunity, B cells also regulate many other functions essential for immune homeostasis. Of major importance, B cells are required for the initiation of T-cell immune responses by B cells antigen presenting and cytokines secreting. In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, and not from bone marrow as commonly believed.

What is The B Cell Differentiation?

The differentiation process of mammalian B cells can be divided into five stages: pre-B cells, immature B cells, mature B cells, activated B cells, and plasma cells. Among them, the differentiation of pre-B cells and immature B cells is antigen-untrusted, and the differentiation process is performed in the bone marrow. The antigen-dependent phase refers to mature B cells that are activated after antigen stimulation and continue to differentiate into plasma cells that synthesize and secrete antibodies. This stage of differentiation is mainly performed in peripheral immune organs.

Some of the activated B-cells become memory B-cells, which have very long lives in the bone marrow, lymph nodes and spleen. They remember the antigen they are specific for and are ready to respond quickly if they see it again. These are the cells that give us long-lasting immunity to different invaders. (Figure 1).

 

Bag3 recombinant monoclonal antibody
A5408 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Bag3 for WB, IHC,ELISA

Menin recombinant monoclonal antibody
A5409 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Menin for WB, IF,ELISA

APE1 recombinant monoclonal antibody
A5410 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human APE1 for WB, IHC,ELISA

ITCH recombinant monoclonal antibody
A5412 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human ITCH for WB,ELISA

HEC1 recombinant monoclonal antibody
A5413 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human HEC1 for WB,ELISA

ADORA1 recombinant monoclonal antibody
A5415 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human ADORA1 for WB, IHC,ELISA

KIF3A recombinant monoclonal antibody
A5416 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human KIF3A for WB, IHC,ELISA

GLUR recombinant monoclonal antibody
A5417 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human GLUR for WB,ELISA

DDX58 recombinant monoclonal antibody
A5418 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human DDX58 for WB, IHC,ELISA

IRAK4 recombinant monoclonal antibody
A5419 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human IRAK4 for WB, IHC, IF,ELISA

Grp75 recombinant monoclonal antibody
A5420 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Grp75 for WB, IHC, IF,ELISA

CRMP2 recombinant monoclonal antibody
A5421 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human CRMP2 for WB, IHC,ELISA

Caspr recombinant monoclonal antibody
A5422 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Caspr for WB, IHC,ELISA

IDH2 recombinant monoclonal antibody
A5423 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human IDH2 for WB, IHC,ELISA

BCHE recombinant monoclonal antibody
A5425 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human BCHE for WB,ELISA

DARPP32 recombinant monoclonal antibody
A5426 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human DARPP32 for WB, IHC,ELISA

Osteopontin recombinant monoclonal antibody
A5427 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Osteopontin for WB,ELISA

PSD95 recombinant monoclonal antibody
A5428 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human PSD95 for WB, IHC,ELISA

SHP1 recombinant monoclonal antibody
A5429 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human SHP1 for WB, IHC,ELISA

Fibrillarin recombinant monoclonal antibody
A5431 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Fibrillarin for WB, IF,ELISA

ASK1 recombinant monoclonal antibody
A5432 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human ASK1 for WB,ELISA

Dysferlin recombinant monoclonal antibody
A5435 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Dysferlin for WB,ELISA

JAM1 recombinant monoclonal antibody
A5437 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human JAM1 for WB, IHC,ELISA

Cortactin recombinant monoclonal antibody
A5438 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human Cortactin for WB,ELISA

MyD88 recombinant monoclonal antibody
A5440 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human MyD88 for WB,ELISA

MTCO2 recombinant monoclonal antibody
A5441 100ul X 3
EUR 595
Description: A recombinant monoclonal antibody from rabbit against human MTCO2 for WB, IF,ELISA